Autoimmune and infectious skin diseases that target desmogleins

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Autoimmune and infectious skin diseases that target desmogleins

Desmosomes are intercellular adhesive junctions of epithelial cells that contain two major transmembrane components, the desmogleins (Dsg) and desmocollins (Dsc), which are cadherin-type cell-cell adhesion molecules and are anchored to intermediate filaments of keratin through interactions with plakoglobin and desmoplakin. Desmosomes play an important role in maintaining the proper structure an...

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ژورنال

عنوان ژورنال: Proceedings of the Japan Academy, Series B

سال: 2010

ISSN: 0386-2208,1349-2896

DOI: 10.2183/pjab.86.524